This is a somewhat supplement to Johnathan's existing answer.
The height of your chair or stool will likely affect the angle you set your table to. If you're sitting low compared to the desk, you'll likely need the surface more upright in order to have the reach and perspective you'll need. If you are sitting much higher than your desk, then a less inclined surface could work fine.
One of the things I try to shoot for is having a comfortable eye line with the center of my piece. I don't want to lean too far forward or tilt my neck uncomfortably. So, I prefer to put my desk as far upright as it goes, and adjust my seat accordingly. This is the most comfortable set up, in my experience.
However, the more upright you go, the more likely you are to need some sort of clip or way to affix your paper to the desk. If it's a large sheet, it'll probably rest on the bottom ridge. But if you want to place a smaller sheet, such as printer paper, in the center of the desk, it'll (obviously) slide without some help.